| Saxton, PA (Borough) |
| Saxtons River, VT (Village) |
| Saybrook, IL (Village) |
| Saybrook Township, OH (Township) |
| Saylor Township, IA (Township) |
| Sayre, OK (City) |
| Sayre, PA (Borough) |
| Sayreville, NJ (Borough) |
| Scales Mound, IL (Village) |
| Scales Mound Township, IL (Township) |
| Scalp Level, PA (Borough) |
| Scambler, MN (Township) |
| Scammon, KS (City) |
| Scammon Bay, AK (City) |
| Scandia, MN (Township) |
