| Spencer County Schools, KY (District) |
| Spencer School District, WI (District) |
| Spencer Valley Elementary, CA (District) |
| Spencer-E Brookfield, MA (District) |
| Spencer-Owen Community Schools, IN (District) |
| Spencer-van Etten Central School District, NY (District) |
| Spencerport Central School District, NY (District) |
| Spencerville Local School District, OH (District) |
| Sperry, OK (District) |
| Spickard R-Ii, MO (District) |
| Spirit Lake Comm School District, IA (District) |
| Spirit Of Knowledge Charter School (District), MA (District) |
| Spiro, OK (District) |
| Splendora ISD, TX (District) |
| Spokane County, WA (ISD) |
