| Spencerport Central School District, NY (District) |
| Spencerville Local School District, OH (District) |
| Sperry, OK (District) |
| Spickard R-Ii, MO (District) |
| Spirit Lake Comm School District, IA (District) |
| Spirit Of Knowledge Charter School (District), MA (District) |
| Spiro, OK (District) |
| Splendora ISD, TX (District) |
| Spokane County, WA (ISD) |
| Spokane International Academy, WA (District) |
| Spokane R-Vii, MO (District) |
| Spokane School District, WA (District) |
| Spoon River Valley CUSD 4, IL (District) |
| Spooner Area School District, WI (District) |
| Spotswood Public Schools, NJ (District) |
